2003-2007 Laboratory of Dr. Max L. Nibert, Department of Microbiology and Molecular Genetics, Harvard Medical School, Boston, MA. Postdoctoral Fellowship: Genetic
Analysis of Reovirus mu2 Protein and Study of Reovirus-Host Cell
Interaction. Exploring the functions of the virus protein mu2 in infected mammalian cells and how
virus-host cell interaction affects viral replication and virus-induced
cytopathology. Exploring mechanisms of
microbial replication and pathogenesis for reovirus using a combination of genomic,
biochemical, cell biological and molecular approaches. Bringing yeast technologies to the study of
reovirus.
1997-2003 Laboratory of Dr. X.F. Steven Zheng, Department of Pathology and Immunology, Washington University
School of Medicine, St. Louis, MO. Ph.D. Thesis: Regulation of the GATA-Type Transcription
Factor Gln3p by the Target of Rapamycin Protein (TOR). Discovered protein interaction partners for
Gln3p and determined how they regulated Gln3p function and host cell physiology
in relation to the human disease Diabetes and general cell nutrient regulation.
1997 Summer/Fall Laboratory of Dr. Timothy Fleming,
Department of Surgery,Washington University School of
Medicine, St. Louis, MO. Rotation Project: Biochemical Purification of the Cancer
Gene Mammaglobin. Developed protocol to
purify a protein related to breast cancer.
1996 Fall Laboratory of Dr. Michael Caparon, Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO. Project: Genetic Analysis of the
bacterial pathogen Streptococcus pyogenes.
1996 Summer/Fall Laboratory of Dr. H. Mark Johnston,
Department of Genetics, Washington University School of
Medicine, St. Louis, MO. Rotation Project: Yeast Two-Hybrid Genetic Screen to Determine Components in the
Snf3/Rgt2 Glucose Signal Transduction Pathway.
Succeeded in discovering a number of proteins that interacted with
Rgt2. Research was relevant for furthering our
understanding of yeast nutrient networks and human diabetes research.
1995 Laboratory of Dr. Austin J. Cooney, Cell Biology Department, Baylor College of Medicine, Houston, TX.
Project: Isolation of the Reproductive Disease Gene Germ Cell Nuclear Factor
(GCNF). Isolated the human homolog of
GCNF, a gene important for meiosis and development of reproductive cells.
1994 Laboratory of Dr. Gregory Doucette, Population Genetics Department National Marine Fisheries Service, Charleston, SC. Project: Genetic Analysis of Gambierdiscus toxicus, the Marine Organism Responsible for Ciguatera Fish Poisoning.
Determined genetic sequence determinants to distinguish between toxic and
nontoxic strains of Gambierdiscus toxicus that was ultimately used
for furthering protocols to test water supplies around the world for
potential Ciguatera fish poisoning outbreaks.
